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Preheat the oven to 350°F. Set an oven rack in the middle position.
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Whisk together the egg, parsley, garlic, oregano, basil, salt, pepper, garlic and water in a large bowl. Add the meat, cheese, breadcrumbs and mix until just combined. Don't overwork the mix.
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Roll the mixture into uniform golf ball-sized meatballs. Place them on an ungreased baking sheet. Bake for 10-12 minutes, then remove the baking sheet from the oven. Use a metal spatula to turn the meatballs. Put the meatballs back in the oven and cook for another 10 minutes, until they are nicely browned and nearly cooked through.
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Meanwhile, bring the marinara sauce to a simmer in a large skillet. Taste it and adjust the seasoning if needed. Transfer the browned meatballs to the marinara sauce, leaving the fat behind. Cover loosely with a lid and simmer for 10 minutes, until the flavors marry and the meatballs are cooked through.
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While the meatballs are cooking, bring a pot of salted water to a boil. Add the pappardelle and cook until al dente. Drain, then toss with the sauce and meatballs. Optionally, serve topped with fresh basil and more grated cheese.